Vertebrate mRNAs with a 5'-terminal pyrimidine tract are candidates for translational repression in quiescent cells: characterization of the translational cis-regulatory element.

@article{Avni1994VertebrateMW,
  title={Vertebrate mRNAs with a 5'-terminal pyrimidine tract are candidates for translational repression in quiescent cells: characterization of the translational cis-regulatory element.},
  author={Dror Avni and S Shama and Fabrizio Loreni and Oded Meyuhas},
  journal={Molecular and cellular biology},
  year={1994},
  volume={14 6},
  pages={3822-33}
}
The translation of mammalian ribosomal protein (rp) mRNAs is selectively repressed in nongrowing cells. This response is mediated through a regulatory element residing in the 5' untranslated region of these mRNAs and includes a 5' terminal oligopyrimidine tract (5' TOP). To further characterize the translational cis-regulatory element, we monitored the… CONTINUE READING