Vertebrate Sex Steroid Receptors: Evolution, Ligands, and Neurodistribution

  title={Vertebrate Sex Steroid Receptors: Evolution, Ligands, and Neurodistribution},
  author={Giulia Guerriero},
  journal={Annals of the New York Academy of Sciences},
  • G. Guerriero
  • Published 1 April 2009
  • Biology
  • Annals of the New York Academy of Sciences
This review focuses on our current understanding of vertebrate sex steroid receptors, with an emphasis on their evolutionary relationships. These relationships are discussed based on nucleotide and amino acid sequence data, which provide clues to the process by which structure–function relations have originated, evolved, and been maintained over time. The importance of the distribution of sex steroid receptors in the vertebrate brain is discussed using the example of androgen receptor sites and… 
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