Vertebrate GAGA factor associated insulator elements demarcate homeotic genes in the HOX clusters

Abstract

Hox genes impart segment identity to body structures along the anterior-posterior axis and are crucial for the proper development of all organisms. Multiple regulatory elements, best defined in Drosophila melanogaster, ensure that Hox expression patterns follow the spatial and temporal colinearity reflected in their tight genomic organization. However, the… (More)
DOI: 10.1186/1756-8935-6-8

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