Versixanthones A-F, Cytotoxic Xanthone-Chromanone Dimers from the Marine-Derived Fungus Aspergillus versicolor HDN1009.

@article{Wu2015VersixanthonesAC,
  title={Versixanthones A-F, Cytotoxic Xanthone-Chromanone Dimers from the Marine-Derived Fungus Aspergillus versicolor HDN1009.},
  author={Guangwei Wu and Guihong Yu and Tibor Kurt{\'a}n and Attila M{\'a}ndi and Jixing Peng and Xiaomei Mo and Ming Liu and Hui Li and Xinhua Sarah Sun and Jing Li and Tianjiao Zhu and Qianqun Gu and Dehai Li},
  journal={Journal of natural products},
  year={2015},
  volume={78 11},
  pages={2691-8}
}
Six unusual xanthone-chromanone dimers, versixanthones A-F (1-6), featuring different formal linkages of tetrahydroxanthone and 2,2-disubstituted chroman-4-one monomers, were isolated from a culture of the mangrove-derived fungus Aspergillus versicolor HDN1009. The absolute configurations of 1-6, representing the central and axial chirality elements or preferred helicities, were established by a combination of X-ray diffraction analysis, chemical conversions, and TDDFT-ECD calculations. The… CONTINUE READING