Versican upregulation in Sézary cells alters growth, motility and resistance to chemotherapy


Sézary syndrome (SéS) represents a leukemic variant of cutaneous T-cell lymphoma, whose etiology is still unknown. To identify dyregulated genes in SéS, we performed transcriptional profiling of Sézary cells (SCs) obtained from peripheral blood of patients with SéS. We identified versican as the highest upregulated gene in SCs. VCAN is an extracellular… (More)
DOI: 10.1038/leu.2015.103


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@article{Fujii2015VersicanUI, title={Versican upregulation in S{\'e}zary cells alters growth, motility and resistance to chemotherapy}, author={K Fujii and M B Karpova and Kenji Asagoe and Oleg Georgiev and Reinhard Dummer and Mirjana Urosevic-Maiwald}, journal={Leukemia}, year={2015}, volume={29}, pages={2024-2032} }