Versican V0 and V1 guide migratory neural crest cells.

  title={Versican V0 and V1 guide migratory neural crest cells.},
  author={Shilpee Dutt and Maurice Kl{\'e}ber and Mattia Matasci and Lukas Sommer and Dieter Robert Zimmermann},
  journal={The Journal of biological chemistry},
  volume={281 17},
We previously showed the selective expression of the chondroitin sulfate proteoglycans versican V0 and V1 in barrier tissues that impede the migration of neural crest cells during embryonic trunk development (Landolt, R. M., Vaughan, L., Winterhalter, K. H., and Zimmermann, D. R. (1995) Development 212, 2303-2312). To test for an active involvement of these isoforms in the guidance process, we have now established protocols to isolate intact versican V0 and V1 in quantities sufficient for… CONTINUE READING

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