Versican: a versatile extracellular matrix proteoglycan in cell biology.

  title={Versican: a versatile extracellular matrix proteoglycan in cell biology.},
  author={Thomas N Wight},
  journal={Current opinion in cell biology},
  volume={14 5},
Versican is a large extracellular matrix proteoglycan that is present in a variety of tissues. Successful cloning of the gene in man, mouse, cow and chicken has revealed the existence of at least four splice variants of versican, which differ in the size of the core protein and the number of glycosaminoglycan chains. The highly interactive nature of versican provides a basis for its importance as a structural molecule, creating loose and hydrated matrices during key events in development and… CONTINUE READING
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