Verschiedene Induktion der mikrosomalen N- und p-Hydroxylierung von Anilin und N-Äthylanilin bei Kaninchen

  • Gerhard de Lange
  • Published 2004 in
    Naunyn-Schmiedebergs Archiv für Pharmakologie und…

Abstract

The treatment of rabbits with chlorophenothane or phenobarbital stimulated the NADPH-dependent hydroxylations of aniline and N-ethylaniline by isolated liver microsomes to a different degree. The N-hydroxylation of N-ethylaniline was not stimulated. The p-hydroxylation of aniline was increased only to a small degree. The N-hydroxylation of aniline and the p… (More)
DOI: 10.1007/BF00538502

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