Versatility of NaCl transport mechanisms in the cortical collecting duct.

@article{Edwards2017VersatilityON,
  title={Versatility of NaCl transport mechanisms in the cortical collecting duct.},
  author={Aur{\'e}lie Edwards and Gilles Crambert},
  journal={American journal of physiology. Renal physiology},
  year={2017},
  volume={313 6},
  pages={F1254-F1263}
}
The cortical collecting duct (CCD) forms part of the aldosterone-sensitive distal nephron and plays an essential role in maintaining the NaCl balance and acid-base status. The CCD epithelium comprises principal cells as well as different types of intercalated cells. Until recently, transcellular Na+ transport was thought to be restricted to principal cells, whereas (acid-secreting) type A and (bicarbonate-secreting) type B intercalated cells were associated with the regulation of acid-base… CONTINUE READING
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