Versatility of Conviction: Heterochromatin as Both a Repressor and an Activator of Transcription

@article{Eissenberg2000VersatilityOC,
  title={Versatility of Conviction: Heterochromatin as Both a Repressor and an Activator of Transcription},
  author={Joel C. Eissenberg and Arthur J. Hilliker},
  journal={Genetica},
  year={2000},
  volume={109},
  pages={19-24}
}
Heterochromatin is a ubiquitous cytological feature of the eukaryotic nucleus. Since the term ‘heterochromatin’ was coined by Heitz (1928), cytologists have consistently noted differential compaction of chromatin in the interphase nuclei of mitotically active cells in all higher eukaryotes. The functional significance of this difference, however, has remained elusive. The pioneering geneticist H.J. Muller first noted that certain chromosome rearrangements were associated with variegated loss of… CONTINUE READING

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