Versatile synthesis of chiral aminophosphine phosphinites (AMPPs) as ligands for enantioselective hydrogenation

@article{Dubrovina2004VersatileSO,
  title={Versatile synthesis of chiral aminophosphine phosphinites (AMPPs) as ligands for enantioselective hydrogenation},
  author={Natalia V. Dubrovina and Vitali I. Tararov and Zenfira Kadyrova and Axel Monsees and Armin Boerner},
  journal={Synthesis},
  year={2004},
  volume={2004},
  pages={2047-2051}
}
New chiral aminophosphine phosphinite (AMPP) ligands with different P-aryl substituents were prepared from (1R,35,4S)-2-azabicyclo[2.2.1]hept-3-ylmethanol by a new and chemoselective synthetic approach. The ligands showedgood enantioselectivity (up to 91%) in the Rh-catalyzed enantioselective hydrogenation of benchmark substrates. 

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