Versatile multi-functionalization of protein nanofibrils for biosensor applications.
@article{Sasso2014VersatileMO,
title={Versatile multi-functionalization of protein nanofibrils for biosensor applications.},
author={Luigi Sasso and Sandy Suei and Laura J. Domigan and Jackie P. Healy and Volker Nock and M. A. K. Williams and Juliet A Gerrard},
journal={Nanoscale},
year={2014},
volume={6 3},
pages={
1629-34
}
}Protein nanofibrils offer advantages over other nanostructures due to the ease in their self-assembly and the versatility of surface chemistry available. Yet, an efficient and general methodology for their post-assembly functionalization remains a significant challenge. We introduce a generic approach, based on biotinylation and thiolation, for the multi-functionalization of protein nanofibrils self-assembled from whey proteins. Biochemical characterization shows the effects of the…
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