Vero cell platform in vaccine production: moving towards cell culture-based viral vaccines

@article{Barrett2009VeroCP,
  title={Vero cell platform in vaccine production: moving towards cell culture-based viral vaccines},
  author={P. N. Barrett and W. Mundt and O. Kistner and M. Howard},
  journal={Expert Review of Vaccines},
  year={2009},
  volume={8},
  pages={607 - 618}
}
The development of cell culture systems for virus propagation has led to major advances in virus vaccine development. Primary and diploid cell culture systems are now being replaced by the use of continuous cell lines (CCLs). These substrates are gaining increasing acceptance from regulatory authorities as improved screening technologies remove fears regarding their potential oncogenic properties. The Vero cell line is the most widely accepted CCL by regulatory authorities and has been used for… Expand
Host receptors: the key to establishing cells with broad viral tropism for vaccine production
Cell Culture-Derived Influenza Vaccines
Continuous cell lines as a production system for influenza vaccines
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