Verification and quality control of routine hematology analyzers

@article{Vis2016VerificationAQ,
  title={Verification and quality control of routine hematology analyzers},
  author={Jolande Y. Vis and Albert Huisman},
  journal={International Journal of Laboratory Hematology},
  year={2016},
  volume={38}
}
  • J. Vis, A. Huisman
  • Published 1 May 2016
  • Medicine
  • International Journal of Laboratory Hematology
Verification of hematology analyzers (automated blood cell counters) is mandatory before new hematology analyzers may be used in routine clinical care. The verification process consists of several items which comprise among others: precision, accuracy, comparability, carryover, background and linearity throughout the expected range of results. Yet, which standard should be met or which verification limit be used is at the discretion of the laboratory specialist. This paper offers practical… 
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References

SHOWING 1-10 OF 47 REFERENCES
Verification and standardization of blood cell counters for routine clinical laboratory tests.
Quality specification in haematology: the automated blood cell count.
  • M. Buttarello
  • Medicine
    Clinica chimica acta; international journal of clinical chemistry
  • 2004
Evaluation of the fully automated hematological analyzer Mindray BC 6800: comparison with Horiba ABX Pentra DX120
TLDR
The aim of this study was to evaluate the performance of BC-6800 hematology analyzer, a new generation fully automated hematological analyzer in use in this laboratory, and in comparison with ABX Pentra DX120, a reference fully automated Hematology Analyzer used in this lab.
Quality control of automated cell counters.
Comparison of five automated hematology analyzers in a university hospital setting: Abbott Cell-Dyn Sapphire, Beckman Coulter DxH 800, Siemens Advia 2120i, Sysmex XE-5000, and Sysmex XN-2000
TLDR
This is the most comprehensive side-by-side comparison of five current top of the range routine hematology analyzers in the setting of a university hospital central laboratory and shows a good concordance for basic blood count parameters.
Evaluation of the Abbott CELL-DYN 4000 hematology analyzer.
TLDR
The evaluation of leukocyte differential counts indicated an excellent correlation with the manual reference method for neutrophils and lymphocytes, a good correlation for monocytes and eosinophils, and a poor correlation for basophils in samples with low counts, but an improvement of the correlation coefficient was found.
ICSH guidelines for the evaluation of blood cell analysers including those used for differential leucocyte and reticulocyte counting
TLDR
This revision is intended to update the 1994 ICSH guidelines but is updated to include new methods, such as digital image analysis for blood cells, a flow cytometric method intended to replace the reference manual 400 cell differential, and numerous new cell indices not identified morphologically are introduced.
Automated blood cell counts: state of the art.
TLDR
The state of the art regarding traditional and new parameters with emphasis on clinical applications and analytic quality are analyzed regarding the CBC count and leukocyte differential count.
Hematology analyzers: special considerations for pediatric patients.
  • E. Wong
  • Medicine
    Clinics in laboratory medicine
  • 2015
Performance evaluation of the Sysmex haematology XN modular system
TLDR
The Sysmex XN haematology instrument showed reduced sample turnaround time of 10% and reduced number of blood films for examination, 49% less than the XE-2100 without loss of sensitivity with more precise and accurate results on low cell counts.
...
1
2
3
4
5
...