Vergleichende testung therapeutisch bedeutsamer antifibrinolytika in vitro unter berücksichtigung des α2-makroglobulins im plasma

@article{Wuppermann2004VergleichendeTT,
  title={Vergleichende testung therapeutisch bedeutsamer antifibrinolytika in vitro unter ber{\"u}cksichtigung des α2-makroglobulins im plasma},
  author={Th. Wuppermann and Prof. Dr. R. Marx},
  journal={Pharmacologia Clinica},
  year={2004},
  volume={1},
  pages={181-187}
}
We were able to show that in all systems tested α2-macroglobulin increases the inhibitory action of all of the synthetic antifibrinolysins used. It has, in addition to the immediate antiplasmin of plasma, an intense effect that has not been recognized before on the drug-induced inhibition of fibrinolysin. Whether α2-macroglobulin is the only substance effecting the drug-induced antifibrinolytic in plasma remains to be explained. From our results it seems possible that dysproteinemic states… CONTINUE READING