Verapamil and diazoxide antagonism of agonist-induced contractions of aortic strips from normal and spontaneously hypertensive rats (SHR).

@article{Levy1975VerapamilAD,
  title={Verapamil and diazoxide antagonism of agonist-induced contractions of aortic strips from normal and spontaneously hypertensive rats (SHR).},
  author={J V Levy},
  journal={Research communications in chemical pathology and pharmacology},
  year={1975},
  volume={11 3},
  pages={387-404}
}
  • J V Levy
  • Published 1975 in
    Research communications in chemical pathology and…
The vulnerability of aortic strips from 50-52 week old Spontaneously Hypertensive Rats (SHR) and normotensive Wistar-Kyoto (WKY) controls to the inhibitory or relaxing effects of the calcium antagonists verapamil and diazoxide was studied. Verapamil produced concentration-dependent inhibition (antagonism) of KCl, PGE2, and methoxamine-induced contraction of… CONTINUE READING