Venus dye trap catches executioners

@article{Dove2003VenusDT,
  title={Venus dye trap catches executioners},
  author={Alan W. Dove},
  journal={The Journal of Cell Biology},
  year={2003},
  volume={160},
  pages={152 - 153}
}
Tumor cells get primitive hen metastatic tumor cells migrate through connective tissue, they use proteases to chew a path for themselves. This finding led to the development of protease inhibitors as potential cancer therapies, but some animal and human clinical tests of these drugs have been disappointing. Wolf et al., reporting on page 267, may have found one reason why: when proteolysis is inhibited, tumor cells resort to an amoeboid type of movement that allows them to squeeze through… CONTINUE READING