Ventromedial prefrontal cortex supports affective future simulation by integrating distributed knowledge.

@article{Benoit2014VentromedialPC,
  title={Ventromedial prefrontal cortex supports affective future simulation by integrating distributed knowledge.},
  author={Roland G. Benoit and Karl K Szpunar and Daniel L. Schacter},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2014},
  volume={111 46},
  pages={16550-5}
}
Although the future often seems intangible, we can make it more concrete by imagining prospective events. Here, using functional MRI, we demonstrate a mechanism by which the ventromedial prefrontal cortex supports such episodic simulations, and thereby contributes to affective foresight: This region supports processes that (i) integrate knowledge related to the elements that constitute an episode and (ii) represent the episode's emergent affective quality. The ventromedial prefrontal cortex… CONTINUE READING
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Schema representation in patients with ventromedial PFC lesions.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2014

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