Ventrolateral medulla AT1 receptors support arterial pressure in Dahl salt-sensitive rats.

@article{Ito2003VentrolateralMA,
  title={Ventrolateral medulla AT1 receptors support arterial pressure in Dahl salt-sensitive rats.},
  author={Satoru Ito and Makoto Hiratsuka and Kazutoshi Komatsu and Kazuyoshi Tsukamoto and Katsuo Kanmatsuse and Alan F. Sved},
  journal={Hypertension},
  year={2003},
  volume={41 3 Pt 2},
  pages={
          744-50
        }
}
The present study addresses the hypothesis that angiotensin type 1 receptors (AT1Rs) in the rostral ventrolateral medulla (RVLM) contribute to the elevation of mean arterial pressure (MAP) in Dahl salt-sensitive (DS) rats fed a diet with a high NaCl content. Groups of DS or Dahl salt-resistant (DR) rats were fed diets containing either 0.3% NaCl (LNa) or 8% NaCl (HNa) for 3 weeks. Rats were anesthetized with alpha-chloralose, and the effects of microinjecting the AT1R antagonist valsartan (Val… CONTINUE READING

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