Ventricular septal defect with secondary left ventricular-to-right atrial shunt is associated with a higher risk for infective endocarditis and a lower late chance of closure.

@article{Wu2006VentricularSD,
  title={Ventricular septal defect with secondary left ventricular-to-right atrial shunt is associated with a higher risk for infective endocarditis and a lower late chance of closure.},
  author={M H Wu and Jou-kou Wang and Ming-Tai Lin and E Wu and Frank Leigh Lu and S N Chiu and H. C. Lue},
  journal={Pediatrics},
  year={2006},
  volume={117 2},
  pages={e262-7}
}
OBJECTIVE Although ventricular septal aneurysm may diminish or even close the shunt through the ventricular septal defect (VSD), developing a left ventricular-to-right atrial (LV-RA) shunt may be unfavorable. This study sought to clarify this issue on the basis of an extended observation of such patients. METHODS Sixty-eight patients (1201 patient-years) who had small perimembranous VSD and LV-RA shunt and were not operated on before 6 years of age were studied. RESULTS The onset age of LV… CONTINUE READING
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