Ventricular septal and free wall rupture complicating acute myocardial infarction: experience in the Multicenter Investigation of Limitation of Infarct Size.

@article{PohjolaSintonen1989VentricularSA,
  title={Ventricular septal and free wall rupture complicating acute myocardial infarction: experience in the Multicenter Investigation of Limitation of Infarct Size.},
  author={Sinikka Pohjola-Sintonen and J. F. Esteban Muller and Peter H. Stone and Stefan N. Willich and Elliot M. Antman and Vicki G. Davis and Corette Breeden Parker and Eugene Braunwald},
  journal={American heart journal},
  year={1989},
  volume={117 4},
  pages={809-18}
}
Left ventricular rupture was studied in 849 patients enrolled in the Multicenter Investigation of Limitation of Infarct Size. Although documented rupture occurred in only 14 cases (1.7%), it accounted for 14% of in-hospital mortality. Seven of the 14 ruptures occurred within 2 days and 10 within 4 days of the MB-creatine kinase-determined onset of infarction. Three easily determined baseline characteristics defined a set of patients with a markedly increased risk of myocardial rupture. Rupture… CONTINUE READING

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