Ventricular myocyte sarcolemmal Kir6.1/SUR2B potassium channels; A potential effector of cardioprotection

@inproceedings{Chen2018VentricularMS,
  title={Ventricular myocyte sarcolemmal Kir6.1/SUR2B potassium channels; A potential effector of cardioprotection},
  author={Shen Chen},
  year={2018}
}
KATP channels are ubiquitously expressed and are said to couple cellular metabolic state and electrical excitability. The KATP channel complex is composed of two subunits in a hetero-octameric structure, with Kir6 subunit form the pore and sulphonylurea receptors (SUR) as β-subunits. In the heart, KATP channels are considered to be composed of the Kir6.2/SUR2A combination and play a key role in responding to metabolic stress as well as in cardioprotection. It is hypothesised that opening of the… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 460 REFERENCES

Models of excitation-contraction coupling in cardiac ventricular myocytes.

  • Methods in molecular biology
  • 2012
VIEW 9 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…