Ventricular fibrillation: how do we stop the waves from breaking?

  title={Ventricular fibrillation: how do we stop the waves from breaking?},
  author={James N. Weiss and P S Chen and Zhilin Qu and Hrayr S. Karagueuzian and Alan Garfinkel},
  journal={Circulation research},
  volume={87 12},
Combined experimental and theoretical developments have demonstrated that in addition to preexisting electrophysiological heterogeneities, cardiac electrical restitution properties contribute to breakup of reentrant wavefronts during cardiac fibrillation. Developing therapies that favorably alter electrical restitution properties have promise as a new paradigm for preventing fibrillation. 

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