Ventral periaqueductal grey stimulation alters heart rate variability in humans with chronic pain.

@article{Pereira2010VentralPG,
  title={Ventral periaqueductal grey stimulation alters heart rate variability in humans with chronic pain.},
  author={Erlick A. C. Pereira and Guohua Lu and ShouYan Wang and Patrick M. Schweder and Jonathan Hyam and John F. Stein and David J. Paterson and Tipu Z. Aziz and Alexander L. Green},
  journal={Experimental neurology},
  year={2010},
  volume={223 2},
  pages={574-81}
}
BACKGROUND The midbrain periaqueductal grey (PAG) area is important for both pain modulation and cardiovascular control via the autonomic nervous system (ANS). While changes in blood pressure dependent upon dorsal or ventral electrode positioning have been described with PAG deep brain stimulation (DBS), little is known mechanistically about the relationships between pain and cardiovascular regulation in humans. Heart rate variability (HRV) is an established measure of cardiovascular regulation… CONTINUE READING
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