Ventral pallidal injections of a mu antagonist block the development of behavioral sensitization to systemic morphine.

@article{Johnson2000VentralPI,
  title={Ventral pallidal injections of a mu antagonist block the development of behavioral sensitization to systemic morphine.},
  author={Patricia I. Johnson and T. Celeste Napier},
  journal={Synapse},
  year={2000},
  volume={38 1},
  pages={61-70}
}
Acute activation of opioid receptors in the ventral pallidum increases motor behaviors in rats. The present study was designed to investigate the possibility that the ventral pallidum influences motor responses induced by chronic opiate treatments and to examine the receptors that may be involved in such an effect. For five consecutive days, ambulations were quantified after rats received once-daily intraperitoneal (i.p.) injections of morphine (10 mg/kg) or saline following bilateral intra… CONTINUE READING

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