Ventilatory constraints and dyspnea during exercise in chronic obstructive pulmonary disease.

  title={Ventilatory constraints and dyspnea during exercise in chronic obstructive pulmonary disease.},
  author={Pierantonio Laveneziana and Chris M. Parker and Denis O'donnell},
  journal={Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme},
  volume={32 6},
Dyspnea (respiratory difficulty) and activity limitation are the primary symptoms of chronic obstructive pulmonary disease (COPD) and progress relentlessly as the disease advances, contributing to reduced quality of life. In COPD, the mechanisms of dyspnea are multifactorial, but abnormal dynamic ventilatory mechanics are believed to play a central role. In flow-limited patients with COPD, dynamic lung hyperinflation (DH) occurs during exercise and has serious sensory and mechanical… CONTINUE READING
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