Ventilator pattern influences neutrophil influx and activation in atelectasis-prone rabbit lung.

@article{Sugiura1994VentilatorPI,
  title={Ventilator pattern influences neutrophil influx and activation in atelectasis-prone rabbit lung.},
  author={Masatoshi Sugiura and P R McCulloch and Sherry Wren and Ralph Dawson and Alison Barbara Froese},
  journal={Journal of applied physiology},
  year={1994},
  volume={77 3},
  pages={1355-65}
}
Both ventilator pattern and neutrophil activation influence lung injury in adult respiratory distress syndrome (ARDS). We therefore questioned whether ventilator pattern independently affects neutrophil accumulation and function in early ARDS. Thirty-five New Zealand White rabbits were anesthetized, paralyzed, and prepared using sterile techniques. Fifteen surfactant-depleted animals were randomized and ventilated for 4 h using high-frequency oscillatory ventilation (HFO) at 15 Hz with an… CONTINUE READING

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