Ventilation above closing volume reduces pulmonary vascular resistance hysteresis.

@article{Creamer1998VentilationAC,
  title={Ventilation above closing volume reduces pulmonary vascular resistance hysteresis.},
  author={Kevin M. Creamer and Laryssa L McCloud and Lyle E Fisher and Ina C Ehrhart},
  journal={American journal of respiratory and critical care medicine},
  year={1998},
  volume={158 4},
  pages={1114-9}
}
The aim of this study was to determine the relationship of pulmonary vascular resistance (PVR) hysteresis and lung volume, with special attention to the effects of ventilation around closing volume (CV). Isolated, blood-perfused canine left lower lung lobes (LLL) were incrementally inflated and deflated. Airway and pulmonary artery pressures (PAP) were recorded after each stepwise volume change. Constant blood flow was provided (600 ml/min) and the pulmonary vein pressure (PVP) was held… CONTINUE READING

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