Venous oxygen levels during aerobic forearm exercise: An index of impaired oxidative metabolism in mitochondrial myopathy.

@article{Taivassalo2002VenousOL,
  title={Venous oxygen levels during aerobic forearm exercise: An index of impaired oxidative metabolism in mitochondrial myopathy.},
  author={Tanja Taivassalo and Amy A. Abbott and Phil Wyrick and Ronald Gerald Haller},
  journal={Annals of neurology},
  year={2002},
  volume={51 1},
  pages={38-44}
}
A cardinal feature of impaired skeletal muscle oxidative metabolism in mitochondrial myopathies is a limited ability to increase the extraction of O(2) from blood relative to the increase in O(2) delivery by the circulation during exercise. We investigated whether aerobic forearm exercise would result in an abnormal increase in venous effluent O(2) in patients with impaired skeletal muscle oxidative phosphorylation attributable to mitochondrial disease. We monitored the partial pressure of O(2… CONTINUE READING
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