Venom yields from Australian and some other species of snakes

@article{Mirtschin2006VenomYF,
  title={Venom yields from Australian and some other species of snakes},
  author={Peter J. Mirtschin and Nathan Dunstan and Ben Hough and Ewan J. M. Hamilton and Sharna Klein and Jonathan Lucas and David Millar and Frank Madaras and Timothy Nias},
  journal={Ecotoxicology},
  year={2006},
  volume={15},
  pages={531-538}
}
The wet and dry venom yields for most Australian native dangerous snakes and a number of non-Australian species are presented. Snakes from the Pseudonaja genus yielded higher than previously published amounts and suggest reconsideration be given to increasing the volume of antivenom in each vial. Higher percentage solids were obtained from venoms from the 4 cobra species (Naja) and Pseudechis genus included in this series. 
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References

SHOWING 1-10 OF 12 REFERENCES
Brown Snakes (Pseudonaja Genus): Venom Yields, Prothrombin Activator Neutralization and Implications Affecting Antivenom Usage
TLDR
Electrophoretic and Western blotting analyses of their venoms showed significantly lower avidity of Brown snake antivenom (BS-AV) for the prothrombin activator (PA) component than for other venom components, including the neurotoxins.
ANTIVENOM DEVELOPMENT IN AUSTRALIA
TLDR
Evidence of a new novel antivenom is presented, which shows high efficacy in reversing the hemostatic abnormality caused by brown snake envenomation and is also more efficient at reversing overall toxicity.
Toxins not neutralized by brown snake antivenom.
Studies on the venom of Oxyuranus microlepidotus.
TLDR
The Australian Small-scaled Snake, Oxyuranus microlepidotus, is the world's most venomous snake, with a murine LD50 of 0.01 mg/kg and the injected venom:LD50 ratio is 1730, the highest recorded for any snake.
The quantities of venom injected into prey of different size by Vipera palaestinae in a single bite.
TLDR
The size of the prey does not necessarily influence the amount of venom injected by the snake, and in three snakes the mice received three to ten times more than the rats, while in two snakes there was no difference between the amounts injected into either prey.
The mass of venom injected by two elapidae: the taipan (Oxyuranus scutellatus) and the Australian tiger snake (Notechis scutatus).
Efficacy and Potency of Antivenoms in Neutralizing the Procoagulant Effects of Australian Snake Venoms in Dog and Human Plasma
TLDR
Findings support an increase in the dose of antivenom to be used for the treatment of Tiger and especially Brown Snake envenomation complicated by coagulopathy.
The Efficacy of Antivenom in Prevention of Cardiovascular Depression and Coagulopathy Induced by Brown Snake (Pseudonaja) Species Venom
TLDR
The dose of antivenom required to prevent severe cardiovascular depression and coagulopathy induced by Pseudonaja textilis venom was 25 times the current recommended dose for clinical use and a tenfold dose was required to neutralise similar effects induced by pseudonaja affinis venom.
The use of experimental models to study the biting habits of Australian snakes in both “defensive” and “hunting” bites
“Australian Animal Toxins”
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