Venlafaxine ER for the treatment of pediatric subjects with depression: results of two placebo-controlled trials.
@article{Emslie2007VenlafaxineEF, title={Venlafaxine ER for the treatment of pediatric subjects with depression: results of two placebo-controlled trials.}, author={Graham J. Emslie and Robert L. Findling and Paul P. Yeung and Nadia R. Kunz and Yunfeng Li}, journal={Journal of the American Academy of Child and Adolescent Psychiatry}, year={2007}, volume={46 4}, pages={ 479-88 } }
OBJECTIVE
The safety, efficacy, and tolerability of venlafaxine extended release (ER) in subjects ages 7 to 17 years with major depressive disorder were evaluated in two multicenter, randomized, double-blind, placebo-controlled trials conducted between October 1997 and August 2001.
METHOD
Participants received venlafaxine ER (flexible dose, based on body weight; intent to treat, n = 169) or placebo (intent to treat, n = 165) for up to 8 weeks. The primary efficacy variable was the change from…
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