Venezuelan equine encephalitis virus-vectored vaccines protect mice against anthrax spore challenge.

@article{Lee2003VenezuelanEE,
  title={Venezuelan equine encephalitis virus-vectored vaccines protect mice against anthrax spore challenge.},
  author={John D. Lee and Angela G Hadjipanayis and Susan L. Welkos},
  journal={Infection and immunity},
  year={2003},
  volume={71 3},
  pages={1491-6}
}
Anthrax, a disease usually associated with herbivores, is caused by the bacterium Bacillus anthracis. The current vaccine licensed for human use requires a six-dose primary series and yearly boosters and causes reactogenicity in up to 30% of vaccine recipients. A minimally reactogenic vaccine requiring fewer inoculations is warranted. Venezuelan equine encephalitis (VEE) virus has been configured for use as a vaccine vector for a wide variety of immunogens. The VEE vaccine vector is composed of… CONTINUE READING
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