Velocity storage contribution to vestibular self-motion perception in healthy human subjects.

@article{Bertolini2011VelocitySC,
  title={Velocity storage contribution to vestibular self-motion perception in healthy human subjects.},
  author={Giovanni Bertolini and Stefano Ramat and Jean Laurens and Christopher J. Bockisch and Sarah Marti and Dominik Straumann and Antonella Palla},
  journal={Journal of neurophysiology},
  year={2011},
  volume={105 1},
  pages={
          209-23
        }
}
Self-motion perception after a sudden stop from a sustained rotation in darkness lasts approximately as long as reflexive eye movements. We hypothesized that, after an angular velocity step, self-motion perception and reflexive eye movements are driven by the same vestibular pathways. In 16 healthy subjects (25-71 years of age), perceived rotational velocity (PRV) and the vestibulo-ocular reflex (rVOR) after sudden decelerations (90°/s(2)) from constant-velocity (90°/s) earth-vertical axis… 
View on PubMed
jn.physiology.org
73 Citations
Highly Influential Citations
9
Background Citations
36
Methods Citations
10
Results Citations
6

Tables from this paper

73 Citations

Is Vestibular Self-Motion Perception Controlled by the Velocity Storage? Insights from Patients with Chronic Degeneration of the Vestibulo-Cerebellum
TLDR
The results confirm that self-motion perception in response to rotational velocity-steps may be controlled by the same velocity storage network that controls reflexive eye movements and that no additional, e.g. cortical, mechanisms are required to explain perceptual dynamics.
Role of Cerebellum in Motion Perception and Vestibulo-ocular Reflex—Similarities and Disparities
TLDR
It was found that 4-AP reduced the decay time constant, but the amount of reduction in the two processes, perception and VOR, was not the same, suggesting the possibility of nonoverlapping or partially overlapping neural substrates for VOR and perception.
Continuous theta-burst stimulation of the right superior temporal gyrus impairs self-motion perception
TLDR
The hypothesis that the right superior temporal gyrus (STG) is involved in mediating self-motion perception and can be modulated by cTBS is supported.
Roll aftereffects: influence of tilt and inter-stimulus interval
  • B. Crane
  • Psychology, Biology
    Experimental Brain Research
  • 2012
TLDR
Data demonstrate that roll perception can be influenced by small preceding stimuli and tilt causes a persistence of the RAE, which is significant when the subject remained upright after the adapting stimulus.
Targeting head movements in humans: Compensation for disturbance from simultaneous body rotations.
The influence of target distance on perceptual self-motion thresholds and the vestibulo-ocular reflex during interaural translation.
Suprathreshold asymmetries in human motion perception
TLDR
The precision at discriminating SD motion stimuli decreased significantly with age, but there was no difference in OD motion or visual stimuli.
Self-motion sensitivity to visual yaw rotations in humans
TLDR
Results suggest that lower differential thresholds (higher sensitivity) are associated with smaller rotations, because they occur more frequently during everyday experience, and suggest that vection is facilitated by a recent exposure, possibly related to visual motion after-effect.
Accumulation of Inertial Sensory Information in the Perception of Whole Body Yaw Rotation
TLDR
Results indicate that differential thresholds decrease with stimulus duration and asymptotically converge to a constant, positive value, which suggests that the central nervous system accumulates sensory information on self-motion over time, resulting in improved discrimination performances.
Self-motion direction discrimination in the visually impaired
Despite the close interrelation between vestibular and visual processing (e.g., vestibulo-ocular reflex), surprisingly little is known about vestibular function in visually impaired people. In this…
...
...

References

SHOWING 1-10 OF 109 REFERENCES
Inertial representation of angular motion in the vestibular system of rhesus monkeys. I. Vestibuloocular reflex.
1. The spatial organization of the vestibuloocular reflex (VOR) was studied in six rhesus monkeys by applying fast, short-lasting, passive head and body tilts immediately after constant-velocity…
The effect of habituation and plane of rotation on vestibular perceptual responses.
TLDR
The reduction in vestibular responses following prolonged visual and Vestibular stimuli, 1) is likely to occur in velocity storage mechanisms mediating ocular and perceptual responses, 2) may represent a mechanism for reducing the disorientating consequences of visual-vestibular conflict and 3) supports the use of optokinetic stimuli as a treatment for vestibULAR patients.
Vestibular perception of angular velocity in normal subjects and in patients with congenital nystagmus.
TLDR
The similarity of the eye velocity and perceptual responses suggests that these two systems receive a vestibular signal which has been similarly processed, which probably originates in the same brainstem 'velocity storage' integrator.
Responses of monkey vestibular-only neurons to translation and angular rotation.
TLDR
Single-unit recordings were obtained from central vestibular neurons in three monkeys during passive head movements and predicted neurons with discharge patterns similar to those of low- and high-sensitivity neurons.
Vestibular and optokinetic eye movements evoked in the cat by rotation about a tilted axis
  • L. Harris
  • Geology, Biology
    Experimental Brain Research
  • 2004
TLDR
The response found during OVAR was a nystagmus with a bias slow-phase velocity that was sinusoidally modulated that bore no consistent relation to the angular rotation.
Three dimensional eye movements of squirrel monkeys following postrotatory tilt.
TLDR
Three-dimensional squirrel monkey eye movements were recorded during and immediately following rotation around an earth-vertical yaw axis to study interactions between the horizontal angular vestibulo-ocular reflex (VOR) and head orientation, and postrotatory VOR alignment was changed relative to gravity by tilting the head out of the horizontal plane.
EFFECTS OF GRAVITY ON ROTATORY NYSTAGMUS IN MONKEYS *
TLDR
Whether the velocity storage mechanism that is important for visual-vestibular interaction also plays a role in mediating nystagmus induced by rotation about an off-vertical axis is determined.
The dynamics of vertical eye movements in normal human subjects.
TLDR
Upward pursuit was better than downward pursuit and upward slow phases of vestibular nystagmus were poorly inhibited with fixation while downward slow phases were normally inhibited.
The Perception of Translational Motion
TLDR
The vestibular system comprises only one input to perceptual mechanisms related to linear motion, and this is supplemented (particularly at low frequency) by somatic and cognitive cues, and is concluded to be strong similarity to the LVOR.
Model-based study of the human cupular time constant.
TLDR
Using a model-based technique to analyze responses with a clear plateau, peripheral and central vestibular time constants are estimated by double exponential fits to slow phase eye velocity and it is likely that the human cupular time constant is similar to that of the monkey and shorter than previously thought.
...
...