Velocity Fluctuations in Kinesin-1 Gliding Motility Assays Originate in Motor Attachment Geometry Variations.

@article{Palacci2016VelocityFI,
  title={Velocity Fluctuations in Kinesin-1 Gliding Motility Assays Originate in Motor Attachment Geometry Variations.},
  author={Henri Palacci and Ofer Idan and Megan Armstrong and Ashutosh Agarwal and Takahiro Nitta and Henry Hess},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  year={2016},
  volume={32 31},
  pages={
          7943-50
        }
}
Motor proteins such as myosin and kinesin play a major role in cellular cargo transport, muscle contraction, cell division, and engineered nanodevices. Quantifying the collective behavior of coupled motors is critical to our understanding of these systems. An excellent model system is the gliding motility assay, where hundreds of surface-adhered motors propel one cytoskeletal filament such as an actin filament or a microtubule. The filament motion can be observed using fluorescence microscopy… CONTINUE READING
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