VegaMC: A Package Implementing a Variational Piecewise Smooth Model for Identification of Driver Chromosomal Imbalances in Cancer

Abstract

VegaMC enables the detection of driver chromosomal imbalances (deletion, amplification and loss of heterozygosity (LOH)) from array comparative genomic hybridization (aCGH) data. VegaMC performs a joint segmentation of aCGH data coming from a cohort of disease affected patients. Segmented regions are used into a statistical framework to distinguish between… (More)

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Cite this paper

@inproceedings{Morganella2013VegaMCAP, title={VegaMC: A Package Implementing a Variational Piecewise Smooth Model for Identification of Driver Chromosomal Imbalances in Cancer}, author={Sandro Morganella and Michele Ceccarelli}, year={2013} }