Vecuronium and d‐Tubocurarine Combination: Potentiation of Effect

@article{Mirakhur1985VecuroniumAD,
  title={Vecuronium and d‐Tubocurarine Combination: Potentiation of Effect},
  author={Rajinder K. Mirakhur and F. M. Gibson and C. J. Ferres},
  journal={Anesthesia \& Analgesia},
  year={1985},
  volume={64},
  pages={711–714}
}
To evaluate possible potentiation of neuromuscular blocking effect of a combination of vecuronium and d-tubocurarine, cumulative dose-response curves were constructed to compare the potency of this combination with vecuronium arid d-tubocurarine given alone. Teri patients each were given incremental injections of 80 μg/kg d-tubocurarine or 5 μg/kg vecuronium plus 40 μg/kg d-tubocurarine, the data for incremental administration of 10 μg/kg vecuronium being used from our previously published… Expand
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TLDR
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TLDR
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  • J. Stirt
  • Medicine
  • British journal of anaesthesia
  • 1989
TLDR
Recovery to 10, 25, 50 and 90% of control twitch height was significantly faster in the group receiving the combination of drugs, and times to block onset did not differ significantly between the three groups. Expand
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TLDR
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TLDR
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Potentiation of Neuromuscular Blockade in Man Produced by Combinations of Pancuronium and Metocurine or Pancuronium and d‐Tubocurarine
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Combining pancuronium with dTc or with metocurine can provide surgical relaxation or ideal conditions for endotracheal intubation with smaller amounts of each drug than would be anticipated if their effects were simply additive. Expand
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Simultaneous administration of pancuronium and alcuronium was used in surgical patients during nitrous oxide — narcotic — barbiturate anaesthesia in order to determine the intensity of neuromuscularExpand
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