Vav links antigen-receptor signaling to the actin cytoskeleton.

@article{Fischer1998VavLA,
  title={Vav links antigen-receptor signaling to the actin cytoskeleton.},
  author={Klaus D. Fischer and Kerry Tedford and Josef M. Penninger},
  journal={Seminars in immunology},
  year={1998},
  volume={10 4},
  pages={
          317-27
        }
}
The haematopoietic-specific Rho-family guanine-nucleotide exchange factor Vav is a regulator of lymphocyte antigen receptor signaling leading to proliferation of B and T cells, generation of the B1 cell lineage and IL-2 production and maturation in T cells. The specific role it plays in these events, however, has not yet been resolved. Recent findings suggest that Vav is recruited to activated antigen receptors and requires both tyrosine phosphorylation and the presence of activating… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 30 CITATIONS, ESTIMATED 51% COVERAGE

61 Citations

0510'99'03'08'13'18
Citations per Year
Semantic Scholar estimates that this publication has 61 citations based on the available data.

See our FAQ for additional information.

Similar Papers

Loading similar papers…