Vaticanol C, a resveratrol tetramer, activates PPARα and PPARβ/δ in vitro and in vivo

@inproceedings{Tsukamoto2010VaticanolCA,
  title={Vaticanol C, a resveratrol tetramer, activates PPARα and PPARβ/δ in vitro and in vivo},
  author={Tomoko Tsukamoto and Rieko Nakata and Emi Tamura and Yukiko Kosuge and Aya Kariya and Michiko Katsukawa and Satoshi Mishima and Tetsuro Ito and Munekazu Iinuma and Yukihiro Akao and Yoshinori Nozawa and Yuji Arai and Shobu Namura and Hiroyasu Inoue},
  booktitle={Nutrition & metabolism},
  year={2010}
}
BACKGROUND Appropriate long-term drinking of red wine is associated with a reduced risk of cardiovascular disease. Resveratrol, a well-known SIRT1 activator is considered to be one of the beneficial components contained in red wine, and also developed as a drug candidate. We previously demonstrated that resveratrol protects brain against ischemic stroke in mice through a PPARalpha-dependent mechanism. Here we report the different effects of the oligomers of resveratrol. METHODS We evaluated… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 11 extracted citations

Resveratrol Oligomers for the Prevention and Treatment of Cancers

Oxidative medicine and cellular longevity • 2014

References

Publications referenced by this paper.
Showing 1-10 of 29 references

MH: Sirt1 protects against high-fat diet-induced metabolic damage

PT Pfluger, D Herranz, S Velasco-Miguel, M Serrano, Tschöp
Proc Natl Acad Sci • 2008

Sirt1 protects against high-fat diet-induced metabolic damage.

Proceedings of the National Academy of Sciences of the United States of America • 2008
View 2 Excerpts

Similar Papers

Loading similar papers…