Vaticanol C, a phytoalexin, induces apoptosis of leukemia and cancer cells by modulating expression of multiple sphingolipid metabolic enzymes

@article{Inoue2020VaticanolCA,
  title={Vaticanol C, a phytoalexin, induces apoptosis of leukemia and cancer cells by modulating expression of multiple sphingolipid metabolic enzymes},
  author={Chisato Inoue and S. Sobue and N. Mizutani and Y. Kawamoto and Y. Nishizawa and M. Ichihara and T. Takeuchi and F. Hayakawa and M. Suzuki and T. Ito and Y. Nozawa and T. Murate},
  journal={Nagoya Journal of Medical Science},
  year={2020},
  volume={82},
  pages={261 - 280}
}
  • Chisato Inoue, S. Sobue, +9 authors T. Murate
  • Published 2020
  • Chemistry, Medicine
  • Nagoya Journal of Medical Science
  • ABSTRACT Resveratrol (RSV) has recently attracted keen interest because of its pleiotropic effects. It exerts a wide range of health-promoting effects. In addition to health-promoting effects, RSV possesses anti-carcinogenic activity. However, a non-physiological concentration is needed to achieve an anti-cancer effect, and its in vivo bioavailability is low. Therefore, the clinical application of phytochemicals requires alternative candidates that induce the desired effects at a lower… CONTINUE READING
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