Vasorelaxant effect of emodin, an anthraquinone from a Chinese herb.

@article{Huang1991VasorelaxantEO,
  title={Vasorelaxant effect of emodin, an anthraquinone from a Chinese herb.},
  author={H. C. Huang and Christopher R. Lee and P D L Chao and Chen Chen and S H Chu},
  journal={European journal of pharmacology},
  year={1991},
  volume={205 3},
  pages={
          289-94
        }
}
The possible mechanism underlying the vasorelaxant effect of emodin isolated from a Chinese herb, was investigated in this study. Emodin dose dependently relaxed isolated vascular rings of human internal mammary artery and saphenous vein, rabbit thoracic aorta, abdominal aorta and mesenteric artery, and rat thoracic aorta. There were no differences in the sensitivity (IC50) and maximal relaxation between intact and endothelium-denuded preparations of rat aorta. In the presence of emodin (10… Expand
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