Vasorelaxant and hypotensive effects of Allium cepa peel hydroalcoholic extract in rat.

@article{Naseri2008VasorelaxantAH,
  title={Vasorelaxant and hypotensive effects of Allium cepa peel hydroalcoholic extract in rat.},
  author={Mohammad Kazem Gharib Naseri and Maedeh Arabian and Mohammad Badavi and Akram Ahangarpour},
  journal={Pakistan journal of biological sciences : PJBS},
  year={2008},
  volume={11 12},
  pages={1569-75}
}
The aim of present study was to investigate the effect of onion (Allium cepa) peel hydroalcoholic extract (OPE) on rat hypertension induced by high-fructose diet and aorta contractility. The OPE was prepared by maceration method using 70% ethanol. The thoracic aorta from male adult rat (Wistar) was dissected and suspended in Krebs-Henseleit solution under 1 g resting tension. Tissue preparation was contracted by KCl (80 mM) or phenylephrine (Phe, 1 microM) and then the extract was applied… CONTINUE READING