Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations.

Abstract

The dietary polyphenolic compound resveratrol, by activating the protein deacetylase enzyme silent information regulator 2/sirtuin 1 (SIRT1), prolongs life span in evolutionarily distant organisms and may mimic the cytoprotective effects of dietary restriction. The present study was designed to elucidate the effects of resveratrol on cigarette smoke-induced… (More)
DOI: 10.1152/ajpheart.00235.2008

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@article{Csiszr2008VasoprotectiveEO, title={Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations.}, author={Anna Csisz{\'a}r and Nazar Labinskyy and Andrej J Podlutsky and Pawel M. Kaminski and Michael S. Wolin and Cuihua Zhang and Partha Mukhopadhyay and Pal Pacher and Furong Hu and Rafael de Cabo and Praveen Ballabh and Zoltan Ungvari}, journal={American journal of physiology. Heart and circulatory physiology}, year={2008}, volume={294 6}, pages={H2721-35} }