Corpus ID: 7884487

Vasopressin release from the rat hypothalamo-neurohypophysial system: effects of gonadotrophin-releasing hormone (GnRH), its analogues and melatonin.

@article{BoczekLeszczyk2010VasopressinRF,
  title={Vasopressin release from the rat hypothalamo-neurohypophysial system: effects of gonadotrophin-releasing hormone (GnRH), its analogues and melatonin.},
  author={E. Boczek-Leszczyk and B. Stempniak and M. Juszczak},
  journal={Journal of physiology and pharmacology : an official journal of the Polish Physiological Society},
  year={2010},
  volume={61 4},
  pages={
          459-66
        }
}
The influence of gonadotrophin-releasing hormone (GnRH) and its analogues (i.e., agonist and antagonist) on vasopressin (VP) release from the rat hypothalamo-neurohypophysial (H-N) system was studied both in vitro and in vivo. Additionally, it was determined whether the possible response of vasopressinergic neurones to these peptides could be modified by melatonin through a cAMP-dependent mechanism. In this study we demonstrate, for the first time, that the highly selective GnRH agonist (i.e… Expand
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