Vasopressin rapidly stimulates Na entry and Na-K pump activity in quiescent cultures of mouse 3T3 cells.

@article{Mendoza1980VasopressinRS,
  title={Vasopressin rapidly stimulates Na entry and Na-K pump activity in quiescent cultures of mouse 3T3 cells.},
  author={Stanley A. Mendoza and N M Wigglesworth and Enrique 4 Rozengurt},
  journal={Journal of cellular physiology},
  year={1980},
  volume={105 1},
  pages={153-62}
}
Addition of (Arg) vasopressin to quiescent cultures of Swiss 3T3 cells rapidly stimulates an ouabain-sensitive 86Rb uptake. In contrast the hormone has no significant effect on the rate of efflux of this cation from preloaded cells. The stimulation of 86Rb uptake is cycloheximide-insensitive, occurs within minutes of hormone addition and results from an increase in the Vmax of the uptake system. Vasopressin stimulates ion uptake in a concentration-dependent fashion (1--100 ng/ml); oxytocin also… CONTINUE READING

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