Vasopressin or norepinephrine in early hyperdynamic septic shock: a randomized clinical trial

@article{Lauzier2006VasopressinON,
  title={Vasopressin or norepinephrine in early hyperdynamic septic shock: a randomized clinical trial},
  author={François Lauzier and Bruno Levy and Patrice Lamarre and Olivier Lesur},
  journal={Intensive Care Medicine},
  year={2006},
  volume={32},
  pages={1782-1789}
}
ObjectiveTo compare the effects of arginine-vasopressin (AVP) and norepinephrine (NE) on hemodynamic variables, organ dysfunction, and adverse events in early hyperdynamic septic shock.Design and settingRandomized, controlled, open-label trial.Patients and participantsTwenty-three patients with early (12 h) hyperdynamic septic shock in two teaching hospitals.InterventionsAVP (0.04–0.20 U min–1, n = 13) as a single agent or NE (0.1–2.8 μg kg–1 min–1, n = 10) infusion for 48 h to achieve mean… Expand
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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