Vasopressin lowers pulmonary artery pressure in hypoxic rats by releasing atrial natriuretic peptide.

@article{Jin1989VasopressinLP,
  title={Vasopressin lowers pulmonary artery pressure in hypoxic rats by releasing atrial natriuretic peptide.},
  author={Hee Kyung Jin and Yunjia Chen and R. H.-H. Yang and T M McKenna and Robert Max Jackson and Suzanne Oparil},
  journal={The American journal of the medical sciences},
  year={1989},
  volume={298 4},
  pages={227-36}
}
The authors previously demonstrated that arginine vasopressin (AVP) lowers pulmonary artery pressure in rats with hypoxic pulmonary hypertension by activation of the V1 receptor. The pulmonary depressor effect of AVP in hypoxia-adapted rats is not due to its effect on cardiac output. The current study tested two alternative hypotheses: that AVP lowers pulmonary artery pressure in the hypoxia-adapted lung by (1) dilating pulmonary vasculature directly, or (2) releasing atrial natriuretic peptide… CONTINUE READING
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