Vasopressin for cerebral perfusion pressure management in patients with severe traumatic brain injury: preliminary results of a randomized controlled trial.

@article{Haren2013VasopressinFC,
  title={Vasopressin for cerebral perfusion pressure management in patients with severe traumatic brain injury: preliminary results of a randomized controlled trial.},
  author={Robert M Van Haren and Chad M. Thorson and Michael Patrick Ogilvie and Evan J Valle and Gerardo A Guarch and Jassin A Jouria and Alexander M Busko and Leo T Harris and Malcolm Ross Bullock and Jonathan Russell Jagid and Alan Livingstone and Kenneth G. Proctor},
  journal={The journal of trauma and acute care surgery},
  year={2013},
  volume={75 6},
  pages={1024-30; discussion 1030}
}
BACKGROUND After traumatic brain injury (TBI), catecholamines (CAs) may be needed to maintain adequate cerebral perfusion pressure (CPP), but there are no recommended alternative vasopressor therapies. This is an interim report of the first study to test the hypothesis that arginine vasopressin (AVP) is a safe and effective alternative to CAs for the management of CPP in patients with severe TBI. METHODS Since 2008, all TBI patients requiring intracranial pressure monitoring at this Level 1… CONTINUE READING
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