Vasopressin deficiency contributes to the vasodilation of septic shock.

@article{Landry1997VasopressinDC,
  title={Vasopressin deficiency contributes to the vasodilation of septic shock.},
  author={Donald W. Landry and H R Levin and Esther M. Gallant and Robert C Ashton and S Seo and Daniela D'Alessandro and Mehmet C. Oz and Juan A. Oliver},
  journal={Circulation},
  year={1997},
  volume={95 5},
  pages={1122-5}
}
BACKGROUND The hypotension of septic shock is due to systemic vasodilation. On the basis of a clinical observation, we investigated the possibility that a deficiency in vasopressin contributes to the vasodilation of septic shock. METHODS AND RESULTS In 19 patients with vasodilatory septic shock (systolic arterial pressure [SAP] of 92 +/- 2 mm Hg [mean +/- SE], cardiac output [CO] of 6.8 +/- 0.7 L/min) who were receiving catecholamines, plasma vasopressin averaged 3.1 +/- 1.0 pg/mL. In 12… CONTINUE READING
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