Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communication

  title={Vasopressin and oxytocin release within the brain: a dynamic concept of multiple and variable modes of neuropeptide communication},
  author={R. Landgraf and I. Neumann},
  journal={Frontiers in Neuroendocrinology},
  • R. Landgraf, I. Neumann
  • Published 2004
  • Biology, Medicine
  • Frontiers in Neuroendocrinology
  • As exemplified particularly with vasopressin and oxytocin, release of neuropeptides within the brain occurs from dendrites, somata, and axons of neurosecretory neurons; mechanisms include activation of intracellular Ca2+ stores, changed strength of synaptic input and altered interaction between transcription factors and gene promoters. Upon demand, both diffuse spread of neuropeptides in the extracellular fluid following dendritic release and focal release from axonal terminals may contribute… CONTINUE READING
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