Vasopressin- and oxytocin-immunoreactive hypothalamic neurones of inbred polydipsic mice.

@article{Ison1993VasopressinAO,
  title={Vasopressin- and oxytocin-immunoreactive hypothalamic neurones of inbred polydipsic mice.},
  author={Angela Ison and Kazunari Yuri and Yoichi Ueta and Gareth Leng and Kiyomi Koizumi and Hiroshi Yamashita and Megumi Kawata},
  journal={Brain research bulletin},
  year={1993},
  volume={31 3-4},
  pages={405-14}
}
In the late 1950s the inbred polydipsic mice, STR/N, was discovered. The early studies indicated that the extreme polydipsia was not due to a lack of vasopressin but probably due to innate thirst of unknown origin. Because the recent investigation has revealed the presence of some functional abnormality in the brain of the STR/N mouse, we now investigated, using immunohistochemical techniques, distribution of vasopressin (AVP)- and oxytocin (OXT)-containing neurones in the hypothalamus of… CONTINUE READING

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